LUNG CANCER NGS PANEL

  • Targeted NGS solution which enables the detection of SNVs,indels (short insertions and deletions), CNVs including gene amplifications and deletions and translocations in lung cancer relevant genes with a single DNA workflow.
  • Target genes and mutation types were selected based on NCCN, CAP, and ESMO guidelines to detect key somatic variants in non-small cell lung cancer (NSCLC).
  • The Panel size is 225Kb which covers the coding exons of 14 genes for detection of SNVs/indels, 5 genes for CNVs and 5 genes for translocations.

Targeted variant types

● SNV/indel
■ CNV
◆ Translocation
AKT1 ●
ALK ●
BRAF ●
CD274 ■
DDR2 ●
EGFR ●
ERBB2 ■ ●
FGR1 ■
FGFR3 ◆
KRAS ●
MEK1 ●
MET ■ ●
NRAS ●
NTRK1 ◆
PIK3CA ●
PTEN ● ■
RET ◆
ROS1 ◆
STK11 ●
TP53 ●
  • Specifically optimized for low input
  • Enables the detection of low frequency variants ie SNVs, translocations as low as 1%.
  • Offers clonal-level resolution of copy number variations and cnLOH (copy-neutral loss of heterozygosity) in genetically diverse tumor populations.
  • Easily tailor the gene panel to fit specific diagnostic or research needs.