• Targets 3.98M CpG sites through 123 Mb of genomic content to target biologically relevant methylation markers.

• While microarrays are still cost-effective and widely used for high-throughput studies involving known CpG sites, they are constrained by their limited content and lower sensitivity in detecting methylation extremes.

• This NGS-based targeted enrichment methylome panel, offers expanded content, single-base resolution, and improved sensitivity, accurately detecting differentially methylated regions (DMRs) across the entire genome, even in low or high methylation extremes. This approach enables more comprehensive methylome analysis and the discovery of novel epigenetic targets, offering superior precision compared to microarrays.

• Expansive content makes this panel an ideal choice to explore the methylation fraction in a diverse range of applications from cancer metastasis, human development, and functional genomics.

• High capture efficiency increases the sensitivity of detection across the footprint of the epigenome while decreasing sequencing costs. The panel is ideal for screening cohort samples and differentially methylated region discovery.